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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXOC1
All Species:
19.7
Human Site:
S561
Identified Species:
33.33
UniProt:
Q9NV70
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NV70
NP_001020095.1
894
101982
S561
D
L
D
G
G
T
L
S
R
Q
H
N
C
G
T
Chimpanzee
Pan troglodytes
XP_001142521
886
101061
S553
D
L
D
G
G
T
L
S
R
Q
H
N
C
G
T
Rhesus Macaque
Macaca mulatta
XP_001087347
894
101935
S561
D
L
D
G
G
T
L
S
R
Q
H
N
C
G
T
Dog
Lupus familis
XP_532380
894
102004
S561
D
L
D
G
G
P
F
S
R
Q
H
N
A
G
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8R3S6
894
101859
S561
D
L
D
G
G
S
L
S
R
Q
H
S
S
G
T
Rat
Rattus norvegicus
NP_001019941
681
76652
W394
R
Y
A
K
L
M
E
W
L
K
S
T
D
Y
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506171
894
101975
S561
E
M
D
G
G
V
F
S
R
S
H
N
P
S
A
Chicken
Gallus gallus
XP_001232097
895
102211
L561
E
E
M
D
G
G
N
L
S
R
S
Y
I
P
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_955891
892
101963
R562
S
D
G
L
M
H
S
R
P
V
S
E
H
R
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVG4
889
102677
D576
I
D
R
Q
I
N
E
D
V
R
K
L
M
M
G
Honey Bee
Apis mellifera
XP_396967
859
98113
K535
S
V
T
S
T
A
S
K
K
L
E
R
Q
V
N
Nematode Worm
Caenorhab. elegans
Q20678
848
97279
E526
S
L
G
G
R
S
M
E
K
H
M
N
E
Q
V
Sea Urchin
Strong. purpuratus
XP_787291
869
100242
S543
A
D
Q
V
D
G
G
S
F
S
R
Y
K
K
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SX85
887
100046
K576
E
T
D
K
K
P
G
K
N
S
P
D
L
T
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.2
99.5
98.5
N.A.
97.1
70.9
N.A.
95
94
N.A.
84.6
N.A.
40.1
42
34.3
49.1
Protein Similarity:
100
98.2
100
98.8
N.A.
98.6
73.8
N.A.
97.1
96.6
N.A.
91.6
N.A.
62.4
62.5
54.5
68.7
P-Site Identity:
100
100
100
73.3
N.A.
80
0
N.A.
46.6
6.6
N.A.
0
N.A.
0
0
20
6.6
P-Site Similarity:
100
100
100
73.3
N.A.
93.3
6.6
N.A.
60
20
N.A.
0
N.A.
6.6
13.3
40
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
0
8
0
0
0
0
0
0
8
0
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
22
0
0
% C
% Asp:
36
22
50
8
8
0
0
8
0
0
0
8
8
0
0
% D
% Glu:
22
8
0
0
0
0
15
8
0
0
8
8
8
0
0
% E
% Phe:
0
0
0
0
0
0
15
0
8
0
0
0
0
0
0
% F
% Gly:
0
0
15
50
50
15
15
0
0
0
0
0
0
36
22
% G
% His:
0
0
0
0
0
8
0
0
0
8
43
0
8
0
15
% H
% Ile:
8
0
0
0
8
0
0
0
0
0
0
0
8
0
0
% I
% Lys:
0
0
0
15
8
0
0
15
15
8
8
0
8
8
0
% K
% Leu:
0
43
0
8
8
0
29
8
8
8
0
8
8
0
0
% L
% Met:
0
8
8
0
8
8
8
0
0
0
8
0
8
8
0
% M
% Asn:
0
0
0
0
0
8
8
0
8
0
0
43
0
0
8
% N
% Pro:
0
0
0
0
0
15
0
0
8
0
8
0
8
8
0
% P
% Gln:
0
0
8
8
0
0
0
0
0
36
0
0
8
8
0
% Q
% Arg:
8
0
8
0
8
0
0
8
43
15
8
8
0
8
0
% R
% Ser:
22
0
0
8
0
15
15
50
8
22
22
8
8
8
0
% S
% Thr:
0
8
8
0
8
22
0
0
0
0
0
8
0
8
29
% T
% Val:
0
8
0
8
0
8
0
0
8
8
0
0
0
8
15
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
15
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _